Nature Protocols is a definite step forward toward open source science. The protocols are peer-reviewed and open for comments. I really like the troubleshooting tables.
Nature Protocols is an interactive online resource for laboratory protocols for bench researchers. Protocols are presented in a 'recipe' style providing step-by-step descriptions of procedures that users can take to the lab bench and immediately apply in their own research. Protocols on the site are fully searchable and organized into logical categories to be easily accessible to researchers.From The Sceptical Chymist